Impulserne i disse nervefibrene er veldig kjappe. Etter at vi har fjernet hånden fra den varme gjenstanden, føler vi den dype smerten som sendes via andre nervefibre som kalles C-fibrene.Karst et al påpeker i sin studie at guy ofte må about doser på ten mg THC per dag for å få appropriate reduksjon i smerter 38, noe som for øvrig fortsatt l
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